Hamdan and Obeidat (2006) reported the case of a 6-year-old boy with tubulo-interstitial nephritis and uveitis (TINU) syndrome. He presented with a 4-month history of anorexia, weight loss and fatigue. After 2 months of corticosteroid therapy, resolution of the uveitis was almost complete but renal function showed only partial improvement. He was still in renal failure 6 months after diagnosis, but there was no relapse of the uveitis.

Mortajil et al., 2006 reported two female patients with severe renal failure of acute onset with the first patient requiring hemodialysis. Acute tubulointerstitial nephritis was diagnosed in both cases and both patients were started on oral steroids at a dose of 1 mg/kg/day. Progressive improvement in renal function was noticed in both patients. The patients presented with bilateral anterior uveitis three months later, which required local corticosteroid therapy. The cause of the interstitial nephritis and the uveitis was unclear in both the cases. Normal renal function was restored in these patients after 24 and 27 months of follow-up, respectively.

Ben Hamida et al. (1995) report the case of a 35-year-old man who was admitted to the hospital for acute renal failure, arthralgia and anterior uveitis. The infectious and the immunological investigations were negative. The ocular examination shows bilateral anterior uveitis. The renal biopsy revealed acute tubulo-interstitial nephritis. He was treated by prednisone (0.5 mg/Kg/day) and subsequently his clinical course was favorable.