The ADGRB2 gene encodes Adhesion G Protein-Coupled Receptor B2, a seven-span transmembrane orphan receptor belonging to the secretin receptor family. This protein, also known as BAI2, is found specifically in the brain and functions as an inhibitor of angiogenesis. It is involved in the G protein-coupled receptor signaling pathway and the cell surface receptor signaling pathway. Based on its function and localization, it is believed to play a role in the positive regulation of synapse assembly and peripheral nervous system development.