The CTNNA2 gene encodes Catenin Alpha-2, a protein involved in cell-cell and cell-matrix adhesion by anchoring cadherin adhesion receptors to the cytoskeleton. While the protein is yet to be fully characterized, studies of its mouse ortholog gene have helped elucidate its function in the nervous system. CTNNA2 is hence believed to play a role in axonogenesis, dendrite morphogenesis, prepulse inhibition and the regulation of synapse structural plasticity.