Membranoproliferative Glomerulonephritis, X-Linked

Alternative Names

  • Mesangiocapillary Glomerulonephritis, X-Linked
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WHO-ICD-10 version:2010

Diseases of the genitourinary system

Glomerular diseases

OMIM Number

305800

Mode of Inheritance

? X-linked predisposition

Description

X-linked mesangiocapillary glomerulonephritis is a kidney disorder causing decreased kidney function because of inflammation and changes in the tissues of the internal kidney structures. It is histologically characterized by intense glomerular hypercellularity, mainly due to mesangial proliferation, and diffuse thickening of the glomerular basement membrane with the appearance of 'double contours'. 

Epidemiology in the Arab World

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Other Reports

Saudi Arabia

In 2003, Kari reported the spectrum of membranoproliferative glomerulonephritis in eight Arab patients from Saudi Arabia with membranoproliferative glomerulonephritis type I and type II. Three patients were siblings and their parents were second-degree cousins. Another patient had a brother who had a renal failure following steroid resistant nephrotic syndrome (SRNS), but the histological cause of his SRNS was not known. 

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