Principal features of the Nablus mask-like facial syndrome include, striking, expressionless, facial appearance with a long face; upswept frontal hairline with normal hair; tight glistening facial skin with small palpebral fissures; apparent hypertelorism; sparse almost absent eyebrows, bulbous nose with prominent columella; long upper and everted lower lip; maxillary hypoplasia; longitudinal cheek dimples; and abnormal posteriorly angulated ears without lobules. Other parts of the body including skin, nails, and genitalia are unremarkable. Worldwide, only few cases are reported in the literature with this syndrome to date.