Cutis marmorata telangiectatica congenita is a benign congenital vascular anomaly characterised by persistent cutis marmorata, telangiectasia, and phlebectasia and often associated with skin atrophy and ulceration. The cutaneous lesions commonly occur on the legs, arms, and trunk and rarely involve the face and scalp. Associated abnormalities such as body asymmetry, vascular and neurological anomalies, glaucoma, macrocephaly, and psychomotor retardation occur in many patients. The diagnosis is mainly clinical, and prognosis is generally good, with cutaneous lesions improving during infancy. There is no specific treatment, and long term follow up is indicated with associated abnormalities.
Fewer than 300 cases of CMTC had been reported in the world literature; many such cases occur sporadically and very rare cases are familial.
Manikoth et al. (2005) described a baby boy born to non-consanguineous parents with skin lesions of generalized persistent cutis marmorata, dilated superficial veins, and telangiectasia involving the limbs, trunk, and scalp. The lesions spared the palms and soles. The rest of the examination, including ultrasound scans of the abdomen and the head, and echocardiogram were normal.