Protein Kinase N2

Alternative Names

PKN2
Protein Kinase C-Like 2
PRKCL2
Protein-Kinase C-Related Kinase 2
PRK2
PAK2, Rat, Homolog Of

Length

152,017 bases

No. of Exons

No. of isoforms

Protein Name

Serine/threonine-protein kinase N2

Molecular Mass

112035 Da

Amino Acid Count

984

Genomic Location

chr1:88,684,238-88,836,254

Gene Map Locus

1p22.2

Description

PKN2 gene encodes serine/threonine-protein kinase N2 (PKN gamma), which is enzyme involved in intracellular signal transduction, cell adhesion, apoptosis, cell migration, and regulation of cytokinesis. PKN gamma is a Rho/Rac effector protein, and it related to PKC (Protein Kinase C) family of protein.

Epidemiology in the Arab World

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United Arab Emirates

Variant Name	Country	Genomic Location	Clinvar Clinical Significance	CTGA Clinical Significance	Condition(s)	HGVS Expressions	dbSNP	Clinvar
NR_110682.1:n.41+27404=	United Arab Emirates	NC_000001.11:g.88657760=		Association	Type 2 Diabetes Mellitus; Obesity	NR_110682.1:n.41+27404=	6699417

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External Links

https://www.genecards.org/cgi-bin/carddisp.pl?gene=pkn2

Contributors

Asha Deepthi: 24.08.2021

Edit History

Pratibha Nair: 09.02.2023
Asha Deepthi: 24.08.2021

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