Zinc Finger- and BTB Domain-Containing Protein 38

Alternative Names

  • ZBTB38
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OMIM Number

612218

NCBI Gene ID

253461

Uniprot ID

Q8NAP3

Length

125,607 bases

No. of Exons

27

No. of isoforms

1

Protein Name

Zinc finger and BTB domain-containing protein 38

Molecular Mass

134257 Da

Amino Acid Count

1195

Genomic Location

chr3:141,324,185-141,449,791

Gene Map Locus
3q23

Description

The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [From RefSeq]

Epidemiology in the Arab World

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Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_001080412.2:c.-416-144A>GUnited Arab EmiratesNC_000003.12:g.141386728A>GAssociationType 2 Diabetes Mellitus; ObesityNG_021426.1:g.67516A>G; NM_001080412.2:c.-416-144A>G; NP_001073881.2:p.?724016
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