Cadherin 15

Alternative Names

  • CDH15
  • Cadherin, Muscle
  • M-Cadherin
  • MCAD
  • CDHM
  • CDH14, Formerly
  • CDH3, Formerly
Back to search Result
OMIM Number

114019

NCBI Gene ID

1013

Uniprot ID

P55291

Length

23,745 bases

No. of Exons

14

No. of isoforms

1

Protein Name

Cadherin-15

Molecular Mass

88916 Da

Amino Acid Count

814

Genomic Location

chr16:89,171,747-89,195,491

Gene Map Locus
16q24.3

Description

This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [From RefSeq]

Epidemiology in the Arab World

View Map
Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_004933.3:c.2324G>AUnited Arab EmiratesNC_000016.10:g.89195034G>ALikely BenignLikely BenignNG_012055.1:g.28280G>A; NM_004933.3:c.2324G>A; NP_004924.1:p.Arg775Gln201368808377635
© CAGS 2024. All rights reserved.