Vesicle-Associated Membrane Protein 8

Alternative Names

  • VAMP8
  • Endobrevin
  • Synaptobrevin-Like, Endosome-Associated
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OMIM Number

603177

NCBI Gene ID

8673

Uniprot ID

Q9BV40

Length

4,497 bases

No. of Exons

4

No. of isoforms

1

Protein Name

Vesicle-associated membrane protein 8

Molecular Mass

11438 Da

Amino Acid Count

100

Genomic Location

chr2:85,577,534-85,582,030

Gene Map Locus
2p11.2

Description

This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.[From RefSeq]

Epidemiology in the Arab World

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Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_003761.4:c.*143T>CUnited Arab EmiratesNC_000002.12:g.85581859T>CBenignAssociationCoronary Artery Disease, Autosomal Dominant, 1NG_022887.1:g.9369T>C; NM_003761.4:c.*143T>C; NP_003752.2:p.?10101182311
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