Meenagh et al. (2002) used PCR-SSOP method to detect the frequencies of IL2 polymorphisms in different populations, in order to identify global allelic variation and to establish a databank for future studies. Along with the other populations, 80 healthy Omani blood and bone marrow donors were also used in the study. Genomic DNA from these subjects was PCR amplified and resolved. Oligonucleotide probes were used to identify the regions of SNPs by subjecting the PCR products to hybridization with digoxigenin-labeled probes and chemiluminescent detection procedures. Chi-squared test was used to compare allele and genotype frequencies between the populations studied. Departures from Hardy-Weinberg equilibrium were tested by chi-squared goodness of fit test, which revealed a significant departure for the IL-2 (T330G) polymorphism in the Omani population. The T and G allele distributions for this polymorphism were 56.9% and 43.1%, respectively; similar to those seen in the North Irish, Singapore Chinese, and Mexican populations. The TT genotype predominated in this population with a frequency of 40%, followed by TG, and GG (33.8 % and 26.2%, respectively).