Najjar et al (1973) were the first to report a syndrome of incompletely developed external genitals, mental retardation, and an ill-defined cardiomyopathy in three brothers born to second cousin Lebanese parents. Later, Najjar et al (1984) described another pair of siblings with a more severe phenotype, with a more severe genital anomaly and an earlier onset of cardiomyopathy. Intellectual disability was not found in this family. 

Malouf et al (1985) described two lebanese sisters, born to first cousin consanguineous parents, who presneted with primary hypergonadotropic hypogonadism and congestive cardiomyopathy.