SLC45A1 gene encodes a protein belonging to the glycoside-pentoside-hexuronide cation symporter transporter family. While the strongest expression of this gene is seen in the brain, it is also expressed in the adult heart, muscle and kidney as well as the fetal brain, kidney and lung. SLC45A1 protein is an integral component of the membrane and due to its symporter activity, it is involved in transmembrane carbohydrate transport. Specifically, the SLC45A1 protein is believed to mediate the uptake of glucose along the pH gradient.