Spermatogenic failure-60 (SPGF60) is characterized by male infertility due to nonobstructive azoospermia. Testicular biopsy shows maturation arrest before the pachytene stage. [From OMIM]
Diseases of the genitourinary system
Diseases of male genital organs
Autosomal recessive
16q22.1
Spermatogenic failure-60 (SPGF60) is characterized by male infertility due to nonobstructive azoospermia. Testicular biopsy shows maturation arrest before the pachytene stage. [From OMIM]
| Subject ID | Country | Sex | Family History | Parental Consanguinity | HPO Terms | Variant | Zygosity | Mode of Inheritance | Reference | Remarks |
|---|---|---|---|---|---|---|---|---|---|---|
| 619646.G.1 | Saudi Arabia | Male | Non-obstructive azoospermia Non-obstructive azoospermia  | NM_001136505.2:c.733G>A | Homozygous | Autosomal, Recessive | Alhathal et al. 2020 | 2 unrelated Saudi pa... |