Stimulated by Retinoic Acid 8

Alternative Names

  • STRA8

Associated Diseases

Spermatogenic Failure 1
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OMIM Number

609987

NCBI Gene ID

346673

Uniprot ID

Q7Z7C7

Length

26,749 bases

No. of Exons

11

No. of isoforms

1

Protein Name

Stimulated by retinoic acid gene 8 protein homolog

Molecular Mass

36908 Da

Amino Acid Count

330

Genomic Location

chr7:135,231,915-135,258,663

Gene Map Locus
7q33

Description

This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [From RefSeq]

Epidemiology in the Arab World

View Map
Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_001394401.1:c.880-2A>GSaudi ArabiaNC_000007.14:g.135251794A>GLikely PathogenicSpermatogenic Failure 1NM_001394401.1:c.880-2A>G780235054
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