Retinoid X Receptor, Beta

Alternative Names

  • RXRB
Back to search Result
OMIM Number

180246

NCBI Gene ID

6257

Uniprot ID

P28702

Length

7,266 bases

No. of Exons

11

No. of isoforms

2

Protein Name

Retinoic acid receptor RXR-beta

Molecular Mass

56922 Da

Amino Acid Count

533

Genomic Location

chr6:33,193,588-33,200,853

Gene Map Locus
6p21.32

Description

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. [From RefSeq]

Epidemiology in the Arab World

View Map
Variant NameCountryGenomic LocationClinvar Clinical SignificanceCTGA Clinical Significance Condition(s)HGVS ExpressionsdbSNPClinvar
NM_021976.5:c.1091C>TSyriaNC_000006.12:g.33195939G>AUncertain SignificanceNG_023374.1:g.9717C>T; NM_021976.5:c.1091C>T; NP_068811.1:p.Pro364Leu
© CAGS 2024. All rights reserved.