Wingless-Type MMTV Integration Site Family, Member 7B

Alternative Names

WNT7B

Length

56,797 bases

No. of Exons

No. of isoforms

Protein Name

Protein Wnt-7b

Molecular Mass

39327 Da

Amino Acid Count

349

Genomic Location

chr22:45,920,366-45,977,162

Gene Map Locus

22q13.31

Description

This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [From RefSeq]

Epidemiology in the Arab World

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Saudi Arabia

Variant Name	Country	Genomic Location	Clinvar Clinical Significance	CTGA Clinical Significance	Condition(s)	HGVS Expressions	dbSNP	Clinvar
NM_058238.3:c.739C>T	Saudi Arabia	NC_000022.11:g.45923167G>A	Likely Pathogenic	Pathogenic	Microphthalmia, Syndromic 9	NM_058238.3:c.739C>T; NP_478679.1:p.Arg247Trp	1475762618	437886

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External Links

https://www.genecards.org/cgi-bin/carddisp.pl?gene=WNT7B

Contributors

Sayeeda Hana: 05.05.2025

Edit History

Sayeeda Hana: 05.05.2025

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