Junctional epidermolysis bullosa (JEB) is caused by blister formation within the basement membrane and is further classified broadly into generalized JEB and localized JEB. JEB non-Herlitz type, also known as generalized intermediate JEB, falls under the generalized JEB subtype. The non-Herlitz type is less severe and is characterized by localized to generalized blistering, nail dystrophy, scarring alopecia, and mucosal involvement. It is caused by mutations in COL17A1, LAMC2, LAMB3 or LAMA3 genes.