Teebi and Teebi (2005) indicated that Meckel syndrome is frequently diagnosed in Egypt.

Farag et al. (1990) described five Bedouin sibs with Meckel-Gruber syndrome. Teebi et al. (1992) and Teebi (1994) further emphasized the observation that Meckel syndrome is commonly encountered in Kuwait; especially the Bedouin population.

In a review of genetic diversity among Arabs, Teebi and Teebi (2005) indicated that Meckel syndrome has a prevalence of 1:3500 live births in Kuwait.

Suri and Gupta (1998) reported two unrelated neonates with Meckel Gruber's syndrome. [Suri K, Gupta B. Meckel Gruber's syndrome. Oman Med J. 1998; 15(1):34-6.]

Rajab et al. (2005) found that between 1993 and 2002, Meckel-Gruber syndrome was diagnosed in 9 patients, with an observed incidence of 1 in 50,000 births. Similarly, Sawardekar (2005) noted that during a 10-year period in an Omani hospital in Nizwa, twelve children were born with Meckel Gruber Syndrome. 

Al-Gazali et al. (1996) reported a child, born to unrelated parents of Palestinian-Jordanian origin, with typical features of Meckel syndrome. This female child, as well as two previous females born to the family, exhibited posterior encephalocele, polycystic kidneys and no polydactyly. 

In 1997, Zlotogora (1997a) analyzed 2000 Palestinian Arabic families and found that in 98 families at least one individual had congenital hydrocephalus and/or open neural tube defect. In ten of these families, the brain malformation was part of Meckel syndrome. In the same year, Zlotogora (1997b) conducted a survey of 2000 different Palestinian Arab families. In 601 cases, an autosomal recessive disease was diagnosed or strongly suspected. 

Al-Gazali et al. 1999 reported on two cases with autosomal recessive Meckel Syndrome from two families with multiple consanguinity. The patients exhibited posterior encephalocele, postaxial polydactyly and bilateral cystic dysplatic kidneys. 

In a review of genetic diversity among Arabs, Teebi and Teebi (2005) indicated that Meckel syndrome has a prevalence of 1:2000 live births in Jerusalem.

Ramadani and Nasrat (1992) reported a rare case of Meckel-Gruber syndrome in a woman who had three affected offspring in the past with similar condition.

Patel (1992) evaluated 17 patients, age 1 day to 6 years with infantile polycystic kidney disease with ultrasound and other imaging techniques. Few rare findings such as liver cysts, associated Meckel syndrome, renal stone, bilateral vesicoureteric reflux and renal calcification were noted.

Teebi and Teebi (2005) indicated that Meckel syndrome is frequently diagnosed in the Arabian Peninsula.

Boutheina et al. (2000) carried out 43 prenatal diagnoses of lethal urinary tract abnormalities during a five-year-period. The abnormalities encountered included Meckel-Gruber syndrome in 4% of the cases.