SP110 gene encodes a leukocyte-specific nuclear body component named Sp110 nuclear body protein that is known to be involved in transcriptional regulation. Studies have shown high levels of SP110 gene expression in peripheral blood leukocytes and spleen. It has been reported that SP110 could be a nuclear hormone receptor co-activator and it may also be associated with ribosome biogenesis, immuno-regulation and myeloid cell differentiation.
