Ardati and Al Saif (1994) described a Bahraini child with Jervell and Lange-Nielsen syndrome (JLNS). Six of the patient's deceased siblings and a surviving cousin were also reported to have been affected by JLNS. The patient had congenital deafness and ECG of both the patient and his cousin displayed prolonged QT interval. Treatment method using propranolol was ineffective for the patient; however, it reduced the frequency of syncope in patient's cousin.

Schulze-Bahr et al. (1997) performed haplotype analysis with microsatellite markers in a Lebanese family with JLNS. The study failed to establish linkage at LQTS1 (potassium-channel gene KVLQT1 ) that is known to cause JLNS and autosomal-dominant long-QT syndrome. It also ruled out two other ion-channel genes associated with autosomal-dominant long-QT syndrome - HERG (LQTS 2) and SCN5A (LQTS 3). Schulze-Bahr et al. (1997) suggested that JLNS could be genetically heterogeneous, and an unknown LQTS gene may be responsible for causing the disease in the Lebanese family.

Adu-Gyamfi et al. (1991) reported a four-year-old girl with deafness who developed polymorphous ventricular tachycardia upon administering  anesthesia. Prolonged QTc interval in the post-anesthetic ECG and deafness confirmed Jervell and Lange-Nielsen syndrome. The case report emphasise on the deleterious effects of halothane anesthesia in patients with long QTc interval syndrome.

Al Rakaf et al. (1997) described a two patients from a Saudi family with Jervell and Lange-Nielsen Syndrome. The proband was a 3-year-old girl born to second degree consanguineous parents. She presented with recurrent episodes of seizure and syncope. The proband's brother, who was deaf, died at the age of 3 years following repeated syncopal attack.