122700.G.2.4

Subject Variants

Variant NameAllele CountAllele FrequencyAssociated DiseaseAssociated Gene
NM_000771.4:c.1075A>C23

Remarks

23 out of 231 total subjects. Allele carriers of this variant had a significantly lower dosage of warfarin compared to wild type.

Related Subjects

Subject IdCountryHPO TermsSexFamily HistoryParental ConsanguinityRemarks
122700.G.2.1LebanonNo106 out of 231 total subjects. 21 heterozygous subjects were used to determine the effects of variants on Warfarin and Acenocoumarol dosage, which was significantly higher than AA carriers. Studies on groups of alleles were performed [see Esmerian et al. 2011]
122700.G.2.2Lebanon68 out of 231 total subjects. 13 homozygous subjects were used to determine the effects of variants on Warfarin and Acenocoumarol dosage, which was significantly lower than GA and GG carriers.
122700.G.2.3Lebanon52 out of 231 total subjects
122700.G.2.5Lebanon5 out of 231 total subjects
122700.G.2.6Lebanon9 out of 231 total subjects Allele carriers of the c.1075A>C variant had a significantly lower dosage of warfarin compared to wild type.
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