NM_001146274.1:c.450+33966C>T

HGVS Expressions

  • NG_012631.1:g.53341C>T
  • NM_001146274.1:c.450+33966C>T
  • NP_001139746.1:p.?
  • NC_000010.11:g.112998590C>T
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Clinvar Clinical Significance

Risk factor

CTGA Clinical Significance

Association, Likely Benign

Variant Type

Substitution

dbSNP

7903146

Clinvar

7413

Epidemiology in the Arab World

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Subject IDCountry of OriginAllele CountAllele FrequencyCTGA Clinical Significance Condition(s)ReferenceRemarks
125853.G.6.1Lebanon0.424AssociationType 2 Diabetes MellitusMtiraoui et al, 2012 Study with 751 Lebanese T2DM patients
125853.G.6.2Lebanon0.348AssociationMtiraoui et al, 2012 Group consisting of 918 Lebanese control...
125853.G.6.3Tunisia0.492AssociationType 2 Diabetes MellitusMtiraoui et al, 2012 Study with 1470 Tunisian T2DM patients
125853.G.6.4Tunisia0.416AssociationMtiraoui et al, 2012 Group consisting of 838 Tunisian control...
125853.G.7.1Lebanon5870.42AssociationType 2 Diabetes MellitusNemr et al, 2012c Study with 691 T2DM patients
125853.G.7.2Lebanon6390.35Nemr et al, 2012c Group consisting of 919 control subjects
125853.G.14.1Lebanon12010.4AssociationType 2 Diabetes MellitusGhassibe-Sabbagh et al. 2014 Study with 1384 T2DM patients
125853.G.14.2Lebanon14040.4Ghassibe-Sabbagh et al. 2014 Group consisting of 1902 healthy control...
125853.G.27.1United Arab EmiratesNA0.41AssociationType 2 Diabetes Mellitus; ObesityOsman et al. 2018 Group consisting of 464 T2DM patients. S...
125853.G.27.2United Arab EmiratesNA0.33Osman et al. 2018 Group consisting of 415 control subjects...
125853.G.29.1United Arab Emirates760.4Likely BenignSaadi et al. 2008 95 Emiratis with diabetes
125853.G.29.2United Arab Emirates590.4Likely BenignSaadi et al. 2008 85 Emiratis with pre-diabetes
125853.G.29.3United Arab Emirates1400.37Likely BenignSaadi et al. 2008 188 Emirati control subjects
125853.G.33.1United Arab Emirates2230.4223AssociationType 2 Diabetes MellitusAl Ali et al. 2019 264 diabetics (134 males, 130 females)
125853.G.33.2United Arab Emirates1140.373Al Ali et al. 2019 153 healthy subjects (109 females, 44 ma...
601665.G.1Lebanon2160.35AssociationObesityNasreddine et al. 2019 308 Lebanese individuals; Average BMI= 2...
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