La Ribonucleoprotein 7, Transcriptional Regulator

Alternative Names

  • LARP7
  • La Ribonucleoprotein Domain Family, Member 7
  • PTEFB Interaction Protein For 7SK Stability
  • PIP7s

Associated Diseases

Alazami Syndrome
Back to search Result
OMIM Number

612026

NCBI Gene ID

51574

Uniprot ID

Q4G0J3

Length

20,444 bases

No. of Exons

17

No. of isoforms

3

Protein Name

La-related protein 7

Molecular Mass

66899 Da

Amino Acid Count

582

Genomic Location

chr4:112,637,142-112,657,585

Gene Map Locus
4q25

Description

This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [From RefSeq]

Epidemiology in the Arab World

View Map
© CAGS 2025. All rights reserved.