Neurodevelopmental Disorder with Seizures and Nonepileptic Hyperkinetic Movements

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WHO-ICD-10 version:2010

Diseases of the nervous system

Episodic and paroxysmal disorders

OMIM Number

618497

Mode of Inheritance

Autosomal recessive

Gene Map Locus

9q34.3

Description

Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements (NEDNEH) is an autosomal recessive severe neurologic disorder characterized by delayed psychomotor development with inability to walk or speak, early-onset refractory seizures, and nonepileptic hyperkinetic movement disorders, including myoclonus dystonia and dyskinesias. Patients require tube feeding and may die of respiratory failure in childhood or in the second decade. [From OMIM]

Epidemiology in the Arab World

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