Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3

Alternative Names

  • SLC1A3
  • Excitatory Amino Acid Transporter 1
  • EAAT1
  • Glial High Affinity Glutamate Transporter
  • Glutamate/Aspartate Transporter, High Affinity, Sodium-Dependent
  • GLAST1
  • GLAST

Associated Diseases

Episodic Ataxia, Type 6
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OMIM Number

600111

NCBI Gene ID

6507

Uniprot ID

P43003

Length

81,729 bases

No. of Exons

12

No. of isoforms

2

Protein Name

Excitatory amino acid transporter 1

Molecular Mass

59572 Da

Amino Acid Count

542

Genomic Location

chr5:36,606,606-36,688,334

Gene Map Locus
5p13.2

Description

This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.[From RefSeq]

Epidemiology in the Arab World

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