Takayasu Arteritis (TA) is a rare inflammatory disease characterised by large-vessel vasculitis (blood vessel inflammation). It predominantly affects the aorta and the pulmonary artery causing occlusion or aneurysm. TA is also referred as 'pulseless disease' because of the difficulty in detecting pulses in the upper extremities, which may be caused due to vascular narrowing. In approximately 90% of cases, TA appears in patients younger than 30 years with a higher female: male ratio.
Takayasu Arteritis is known to be associated with human lymphocyte antigen (HLA) but the exact nature of how it develops is unknown.