Genetic association study reveals link between a HSD3B1 genotype and type 2 (hormone-independent) endometrial cancer: https://t.co/uDkyFSwzj4 #Cancer #endometrialcancer #breastcancer #prostratecancer #hormone #estrogen #adrenal #genetics #genotype #association #variant

We have almost completed updating the #CTGA database with published data from...

Researchers analyzed mice with mutated KCNC3, created in a forward genetics experiment; the mice exhibited reduced hippocampal activity which critically affected learning and memory: https://t.co/yxqxrJ6x9s #learningdisability #mice #potassium #nerves #neurons #brain #genetics

A recent study shed light on the pathogenesis of Crohn's Disease: Deactivating mutations in SP140, a 'chromatin reading' protein, was shown to cause unrestricted topoisomerase activity, resulting in dysfunctional macrophages: https://t.co/FgTyDf1mQQ #crohnsdisease #crohns #crohn

Study on epigenetics in mice reveal how different levels of SMCHD1 protein, in the mother's egg was shown affect regulation of Hox genes critical for skeletal patterning in the embryo: https://t.co/rCneIwVdeM #epigenome #epigenetics #genetics #regulation #expression #genes #mice

The #CTGA #database continues to grow. We are currently focused on adding...

Study uncovers novel genetic association with a fatal form of pediatric liver disease. Loss-of-function variants in the FOCAD gene was associated with early-onset liver cirrhosis. Read about the study here: https://t.co/4vtFnqsmjl #liver #cirrhosis #genetics #mutations #variant

Recent research into Cystic Fibrosis #treatment utilizes antisense oligonucleotides to circumvent nonsense-mediated mRNA decay and produce partially-functioning CFTR protein: https://t.co/r5xwq2K3QV Check out the main article on Nature: https://t.co/W5hHb7exl0 #cysticfibrosis

The CTGA database is continuously being updated. We are currently focused on...

Study utilizes UK biobank genetic and health data to analyze European ancestry. Analysis of shared genomes revealed three distinct branches of genetic background, from southern, central-eastern, and northwestern Europe: https://t.co/j8F2B9qKZT #population #populationgenetics